The Impact of Diet on Common Skin Disorders
DOI:
https://doi.org/10.6000/1929-5634.2014.03.03.6Keywords:
Psoriasis, acne, atopic dermatitis, allergic contact dermatitis, dietary products, glycemic index, fatty acids, low nickel diet.Abstract
The role of nutrition in the treatment of common dermatoses is often overlooked. Nevertheless, there is a large amount of evidence suggesting that diet may have an important role in the pathogenesis, as well as in determining the clinical course of common skin disorders; including acne, psoriasis, atopic dermatitis and allergic contact dermatitis. Consequently, diet could have significant preventive or therapeutic impact in these skin conditions. Psoriasis, atopic dermatitis and allergic contact dermatitis are chronic relapsing skin disorders characterised by remissions and flare-ups, requiring long-term maintenance therapy. Although acne occurs most commonly during adolescence, and rarely continues into adulthood, it has a large impact on patients' self-confidence and self-image. For each of these skin conditions, a variety of foods may lead to exacerbation of the disease and may have a significant role in increasing the risk of other comorbidities. The aim of this review is to present current knowledge on the relationship between high-fat and high glycemic index diet and acne and psoriasis. Additionally, possible role of nutritional supplementation in such will also be reviewed. And finally, the role of dietary restriction in patients with atopic dermatitis and low nickel diet, in those who are sensitive to nickel, will be discussed. Although future studies are necessary in order to evaluate the effect of diet in these skin disorders, identifying certain foods as a potential factor that could contribute to exacerbation of the disease or to development of further complications can provide important preventive measure.
References
Cordain L, Lindeberg S, Hurtado M, Hill K, Eaton SB, Brand-Miller J. Acne vulgaris: a disease of Western civilization. Arch Dermatol 2002; 138: 1584-1590. http://dx.doi.org/10.1001/archderm.138.12.1584 DOI: https://doi.org/10.1001/archderm.138.12.1584
Rezaković S, Bukvić Mokos Z, Basta-Juzbašić A. Acne and diet: facts and controversies. Acta Dermatovenerol Croat 2012; 20(3): 170-174.
Burris J, Rietkerk W, Woolf K. Acne: the role of medical nutrition therapy. J Acad Nutr Diet 2013; 113(3): 416-430. http://dx.doi.org/10.1016/j.jand.2012.11.016 DOI: https://doi.org/10.1016/j.jand.2012.11.016
Burris J, Rietkerk W, Woolf K. Relationships of self-reported dietary factors and perceived acne severity in a cohort of New York young adults. J Acad Nutr Diet 2014; 114(3): 384-392. http://dx.doi.org/10.1016/j.jand.2013.11.010 DOI: https://doi.org/10.1016/j.jand.2013.11.010
Schaefer O. When the Eskimo comes to town. Nutr Today 1971; 6: 8-16. http://dx.doi.org/10.1097/00017285-197111000-00003 DOI: https://doi.org/10.1097/00017285-197111000-00003
Smith RN, Mann NJ, Braue A, Mächeläinen H, Varigos JA. A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr 2007; 86: (1): 107-115. DOI: https://doi.org/10.1093/ajcn/86.1.107
Pappas A. The relationship of diet and acne: A review. Dermatoendocrinol 2009; 1(5): 262-267. http://dx.doi.org/10.4161/derm.1.5.10192 DOI: https://doi.org/10.4161/derm.1.5.10192
Ferdowsian HR, Levin S. Does diet really affect acne? Skin Therapy Lett 2010; 15(3): 1-25.
Kaymak Y, Adisen E, Ilter N, Bideci A, Gurler D, Celik B. Dietary glycemic index and glucose, insulin-like growth factor-1, insulin-like growth factor binding protein 3, and leptin levels in patients with acne. J Am Acad Dermatol 2007; 57: 819-823. http://dx.doi.org/10.1016/j.jaad.2007.06.028 DOI: https://doi.org/10.1016/j.jaad.2007.06.028
Danby FW. Nutrition and acne. Clinics in Dermatology 2010; 28: 598-604. http://dx.doi.org/10.1016/j.clindermatol.2010.03.017 DOI: https://doi.org/10.1016/j.clindermatol.2010.03.017
Rudman SM, Philpott MP, Thomas GA, Kealey T. The role of IGF-I in human skin and its appendages: morphogen as well as mitogen? J Invest Dermatol 1997; 109: 770-777. http://dx.doi.org/10.1111/1523-1747.ep12340934 DOI: https://doi.org/10.1111/1523-1747.ep12340934
Melnik BC, John SM, Schmitz G. Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: lessons learnt from laron syndrome. Nutr Metab 2011; 8: 41. http://dx.doi.org/10.1186/1743-7075-8-41 DOI: https://doi.org/10.1186/1743-7075-8-41
Costa A, Lage D, Moisés TA. Acne and diet: truth or myth? An Bras Dermatol 2010; 85(3): 346-353. http://dx.doi.org/10.1590/S0365-05962010000300008 DOI: https://doi.org/10.1590/S0365-05962010000300008
Ismail NH, Manaf ZA, Azizan NZ. High glycemic load diet, milk and ice cream consumption are related to acne vulgaris in Malaysian young adults: a case control study. BMC Dermatol 2012; 12: 13. http://dx.doi.org/10.1186/1471-5945-12-13 DOI: https://doi.org/10.1186/1471-5945-12-13
Adebamowo CA, Spiegelman D, Berkey CS, et al. Milk consumption and acne in teenaged boys. J Am Acad Dermatol 2008; 58(5): 787-793. http://dx.doi.org/10.1016/j.jaad.2007.08.049 DOI: https://doi.org/10.1016/j.jaad.2007.08.049
Donnet-Hughes A, Duc N, Serrant P, Vidal K, Schiffrin EJ. Bioactive molecules in milk and their role in health and disease: the role of transforming growth factor-β. Immunol. Cell Biol 2000; 78(1): 74-79. http://dx.doi.org/10.1046/j.1440-1711.2000.00882.x DOI: https://doi.org/10.1046/j.1440-1711.2000.00882.x
Holmes MD, Pollak MN, Willett WC, Hankinson SE. Dietary correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomarkers Prev 2002; 11(9): 852-861.
Kaaks R, Bellati C, Venturelli E, et al. Effects of dietary intervention on IGF-I and IGF-binding proteins, and related alterations in sex steroid metabolism: the Diet and Androgens (DIANA) Randomised Trial. Eur J Clin Nutr 2003; 57(9): 1079-1088. http://dx.doi.org/10.1038/sj.ejcn.1601647 DOI: https://doi.org/10.1038/sj.ejcn.1601647
Logan AC. Linoleic and linolenic acids and acne vulgaris. Br J Dermatol 2008; 158: 201-202.
McCusker MM, Grant-Kels JM. Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. Clin Dermatol 2010; 28(4): 440-451. http://dx.doi.org/10.1016/j.clindermatol.2010.03.020 DOI: https://doi.org/10.1016/j.clindermatol.2010.03.020
Cohen AD, Sherf M, Vidavsky L, Vardy DA, Shapiro J, Meyerovitch J. Association between psoriasis and the metabolic syndrome. Dermatol 2008; 216: 152-155. http://dx.doi.org/10.1159/000111512 DOI: https://doi.org/10.1159/000111512
Neimann AL, Shin DB, Wang X, Margolis D, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol 2006; 55: 829-835. http://dx.doi.org/10.1016/j.jaad.2006.08.040 DOI: https://doi.org/10.1016/j.jaad.2006.08.040
Ricketts JR, Rothe MJ, Grant-Kels JM. Nutrition and psoriasis. Clin Dermatol 2010; 28(6): 615-626. http://dx.doi.org/10.1016/j.clindermatol.2010.03.027
Wolters M. Diet and psoriasis: experimental data and clinical evidence. Br J Dermatol 2005; 153(4): 706-714. http://dx.doi.org/10.1111/j.1365-2133.2005.06781.x DOI: https://doi.org/10.1111/j.1365-2133.2005.06781.x
Rucevic I, Perl A, Barisic-Drusko V, Adam-Perl M. The role of the low energy diet in psoriasis vulgaris treatment. Coll Antropol 2003; 27: 41-48.
Jankovic S, Raznatovic M, Marinkovic J, Jankovic J, Maksimovic N. Risk factors for psoriasis: a case-control study. J Dermatol 2009; 36: 328-334. http://dx.doi.org/10.1111/j.1346-8138.2009.00648.x DOI: https://doi.org/10.1111/j.1346-8138.2009.00648.x
Poikolainen K, Reunala T, Karvonen J. Smoking, alcohol and life events related to psoriasis among women. Br J Dermatol 1994; 130: 473-477. http://dx.doi.org/10.1111/j.1365-2133.1994.tb03380.x DOI: https://doi.org/10.1111/j.1365-2133.1994.tb03380.x
Millsop JW, Bhatia BK, Debbaneh M, Koo J, Liao W. Diet and psoriasis, part III: Role of nutritional supplements. J Am Acad Dermatol 2014; 71(3): 561-569. http://dx.doi.org/10.1016/j.jaad.2014.03.016 DOI: https://doi.org/10.1016/j.jaad.2014.03.016
Kharaeva Z, Gostova E, De Luca C, Raskovic D, Korkina L. Clinical and biochemical effects of coenzyme Q10, Vitamin E, and Selenium supplementation to psoriasis patients. Nutrition 2009; 25: 295-302. http://dx.doi.org/10.1016/j.nut.2008.08.015 DOI: https://doi.org/10.1016/j.nut.2008.08.015
Huckins D, Felson DT, Holick M. Treatment of psoriatic arthritis with oral 1-25 dihydroxyvitamin D3: a pilot study. Arthritis Rheum 1990: 1723-1727. http://dx.doi.org/10.1002/art.1780331117 DOI: https://doi.org/10.1002/art.1780331117
el-Azhary RA, Peters MS, Pittelkow MR, Kao PC, Muller SA. Efficacy of vitamin D3 derivatives in the treatment of psoriasis vulgaris: a preliminary report. Mayo Clin Proc 1993; 68: 835-841. DOI: https://doi.org/10.1016/S0025-6196(12)60690-9
Ricketts JR, Rothe MJ, Grant-Kels JM. Nutrition and psoriasis.Clin Dermatol. 2010; 28(6): 615-26. http://dx.doi.org/10.1016/j.clindermatol.2010.03.027 DOI: https://doi.org/10.1016/j.clindermatol.2010.03.027
Bhatia BK, Millsop JW, Debbaneh M, Koo J, Linos E, Liao W. Diet and psoriasis, part II: celiac disease and role of a gluten-free diet. J Am Acad Dermatol 2014; 71(2): 350-358. http://dx.doi.org/10.1016/j.jaad.2014.03.017 DOI: https://doi.org/10.1016/j.jaad.2014.03.017
Harper CR, Jacobson TA. The fats of life: the role of omega-3 fatty acids in the prevention of coronary heart disease. Arch Intern Med 2001; 161: 2185. http://dx.doi.org/10.1001/archinte.161.18.2185 DOI: https://doi.org/10.1001/archinte.161.18.2185
Cao G, Booth SL, Sadowski JA, Prior RL. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am J Clin Nutr 1998; 68: 1081-1087. DOI: https://doi.org/10.1093/ajcn/68.5.1081
Akesson A, Weismayer C, Newby PK, Wolk A. Combined effect of low-risk dietary and lifestyle behaviors in primary prevention of myocardial infarction in women. Arch Intern Med 2007; 167: 2122. http://dx.doi.org/10.1001/archinte.167.19.2122 DOI: https://doi.org/10.1001/archinte.167.19.2122
Debbaneh M, Millsop JW, Bhatia BK, Koo J, Liao W. Diet and psoriasis, part I: Impact of weight loss interventions. J Am Acad Dermatol 2014; 71(1): 133-140. http://dx.doi.org/10.1016/j.jaad.2014.02.012 DOI: https://doi.org/10.1016/j.jaad.2014.02.012
Kim JS. Pediatric atopic dermatitis: the importance of food allergens. Semin Cutan Med Surg 2008; 27(2): 156-160. http://dx.doi.org/10.1016/j.sder.2008.05.003 DOI: https://doi.org/10.1016/j.sder.2008.05.003
David TJ. Adverse reactions and intolerance to foods. Br Med Bull 2000; 56(1): 34-50. http://dx.doi.org/10.1258/0007142001902950 DOI: https://doi.org/10.1258/0007142001902950
Burks AW, James JM, Hiegel A, et al. Atopic dermatitis and food hypersensitivity reactions. J Pediatr 1988; 132: 132-136. DOI: https://doi.org/10.1016/S0022-3476(98)70498-6
Sicherer SH, Sampson HA. Food hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management. J Allergy Clin Immunol 1999; 104: 114-122. http://dx.doi.org/10.1016/S0091-6749(99)70053-9 DOI: https://doi.org/10.1016/S0091-6749(99)70053-9
Guillet G, Guillet MH. Natural history of sensitizations in atopic dermatitis. Arch Dermatol 1992; 128: 187-192. http://dx.doi.org/10.1001/archderm.1992.01680120059004 DOI: https://doi.org/10.1001/archderm.1992.01680120059004
Kim J, Kwon J, Noh G, Lee SS. The effects of elimination diet on nutritional status in subjects with atopic dermatitis. Nutr Res Pract 2013; 7 (6): 488-494. http://dx.doi.org/10.4162/nrp.2013.7.6.488 DOI: https://doi.org/10.4162/nrp.2013.7.6.488
Romieu I, Trenga C. Diet and obstructive lung diseases. Epidemiol Rev 2001; 23: 268-287. http://dx.doi.org/10.1093/oxfordjournals.epirev.a000806 DOI: https://doi.org/10.1093/oxfordjournals.epirev.a000806
Liu AH, Jaramillo R, Sicherer SH, et al. National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol 2010; 126: 798-806. http://dx.doi.org/10.1016/j.jaci.2010.07.026 DOI: https://doi.org/10.1016/j.jaci.2010.07.026
Zirwas MJ, Molenda MA. Dietary nickel as a cause of systemic contact dermatitis. J Clin Aesthet Dermatol 2009;2 (6): 39-43.
Sharma AD. Low nickel diet in dermatology. Indian J Dermatol 2013; 58(3): 240. http://dx.doi.org/10.4103/0019-5154.110846 DOI: https://doi.org/10.4103/0019-5154.110846
Lu LK, Warshaw EM, Dunnick CA. Prevention of nickel allergy: the case for regulation? Dermatol Clin Apr 2009; 27(2): 155-161. http://dx.doi.org/10.1016/j.det.2008.11.003 DOI: https://doi.org/10.1016/j.det.2008.11.003
Pizzutelli S. Systemic nickel hypersensitivity and diet: myth or reality? Eur Ann Allergy Clin Immunol 2011; 43(1): 5-18.
Mislankar M, Zirwas MJ. Low-nickel diet scoring system for systemic nickel allergy. Dermatitis. 2013; 24(4): 190-195. http://dx.doi.org/10.1097/DER.0b013e3182937e81 DOI: https://doi.org/10.1097/DER.0b013e3182937e81
Ysart G, Miller P, Crews H, et al. Dietary exposure estimates of 30 elements from the UK Total Diet Study. Food Addit Contam 1999; 16: 391. http://dx.doi.org/10.1080/026520399283876 DOI: https://doi.org/10.1080/026520399283876
Downloads
Published
How to Cite
Issue
Section
License
Policy for Journals/Articles with Open Access
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work
Policy for Journals / Manuscript with Paid Access
Authors who publish with this journal agree to the following terms:
- Publisher retain copyright .
- Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work .
